Dr Adrian Bradu is a lecturer in the School of Physical Sciences and a member of the [Applied Optics Group](, where he develops imaging techniques for applications in biosciences and medicine. In particular his research is focused on imaging techniques based on optical coherence tomgraphy, elastography and photo-acoustics.

Adrian began his career at Alexandru Ioan Cuza University, Iasi, graduating in 1997 with an Bsc in Physics. Between 1997 and 1998He moved south to Canterbury for his PhD to work on a joint project with the British Museum, the National Gallery and NTU, developing applications of optical coherence tomography (OCT) in art conservation and archaeology. Changing direction slightly, he moved to Oxford University Hospitals NHS Trust to complete the IPEM Part 1 training programme in medical physics, with rotations in diagnostic radiology, nuclear medicine and radiotherapy.

Returning to the world of optics in late 2011, Michael took up the position of Research Associate in Biophotonics at the Hamlyn Centre, Imperial College London, where he developed endomicroscopy systems for applications in surgery, and later became a Hamlyn Fellow. He moved to the University of Kent as a lecturer in 2017 to develop a research programme in point-of-care and endoscopic microscopy. Dr Adrian Bradu studied for his Msc in Optics, Optoelectronics and Microwaves at École Nationale Supérieure d’Électronique et de Radioélectricité de Grenoble (ENSERG), Grenoble, France; his thesis was ‘Spectrophotometry of turbid media using optical fibre probes’. He went on to complete his PhD in the group of Professor Jacques Derouard at Joseph Fourier University, Grenoble, France in 2004. His thesis title was ‘Optical methods used to investigate biological tissues. Cerebral tissue spectroscopy using small optical fibre probes and optical coherence tomography imaging’.

  • Master slave interferometry. This is a novel method introduced by Prof. Podoleanu and myself last year to produce optical coherence tomography images. We submitted a patent and already published 7 journal papers in this respect.
  • Development of dedicated software to acquire data, display and analysis of the images using cutting-edge techniques and methods for camera, swept source, master-slave interferometry based Optical Coherence Tomography (OCT) systems and not only.
  • Combining principles of spectral interferometry with principles of time domain interferometry to implement novel configurations up to proof of concept, applicable to bio-sensing and cell, tissue imaging or imaging of different organs.
  • Imaging systems, combining a coherence gated wave-front sensors with one or more of the following imaging channels, optical coherence tomography, confocal microscopy, non-linear microscopy and then combining coherence gated wave-front sensing with optical coherence tomography, using different or similar principles of time domain and spectral domain interferometry.
  • Extending the axial range in swept source optical coherence tomography by using re-circulation loops which is a quite hot topic in the OCT community. The motivation of this work is related to the fact that one of the main drawbacks of the swept source optical coherence tomography is its limited axial range. Novel interferometer configurations are tested, equipped in each arm with adjustable path length rings. By compensating for the losses in the rings using semiconductor optical amplifiers, multiple paths A-scans can be obtained which when combined axially, can lead to an extremely long overall axial range. The effect of the re-circulation loops is equivalent with extending the coherence length of the swept source. In this way, the axial imaging range in swept source optical coherence tomography can be extended well beyond the limit imposed by the coherence length of the laser, to exceed in principle many centimetres.
  • Non-invasive imaging of biological tissues: optical coherence tomography and confocal microscopy techniques for biological tissue imaging and adaptive optics techniques for retinal imaging.
  • Spectroscopy of biological media (development, measurements, interpretation; spectroscopic techniques and numerical simulations applied to biological media, optical phantoms preparation and handling).
  • Spectroscopy of the turbid media (development, measurements, interpretation, etc).